Selected speakers
- David M. Andrews, Astra Zeneca
Topic: Oncology research.
- Tomáš Cihlář, Gilead Sciences
Topic: Novel compounds for Ebola treatment
- Dr. Mathias Frederiksen, Novartis Institute for BioMedical Research
Topic: Chemical genetics
- Christian Heinis, EPF Lausanne
Topic: Peptide macrocycle drugs
- Josef Klíma, Pharmakl
Topic: Bioanalytics
- Vít Perlík, PharmInvent
Topic: Clinical research in inhalation drug developmentt
- Marc de la Roche, University of Cambridge
Topic: Canonical and non-canonical targets in epithelial cancer
- Paul Vulto, Managing director and co-founder Mimetas
Topic: Organ on chip technology in drug development
- Sergey Zozulya, Enamine, Inc
Topic: High-throughput screening of compound libraries
Programme
| Monday September 5th | ||
| 16:00 | Registration at Masaryk dormitory | |
| 18:00 | Welcome party at Masaryk dormitory | |
| Tuesday September 6th | ||
| 9:00 | Welcome from the IOCB director & UCT rector | |
| 9:15 | Zdeněk Hostomsky (Director IOCB) Opening Remarks on Pharma Discovery |
|
| 10:00 | Coffee break | |
| 10:30 | Tomáš Cihlář (Gilead Sci) Novel Antivirotics |
|
| 11:15 | Kvido Stříšovský IOCB Regulation of Cellular Signaling by Intramembrane Proteolysis and Protein Trafficking |
|
| 12:00 | Lunch | |
| 13:00 | Marc de la Roche (University of Cambridge) Canonical and Non-canonical Therapeutic Targets in Epithelial Cancers |
|
| 13:45 | James Douglas Engel (University Michigan) Development of Small Molecule Therapeutics to Treat the First Genetic Disease |
|
| 14:30 | Coffee break | |
| 14:45 | Michael Kossenjans (Astra Zeneca) Building a HTS collection |
|
| 15:30 | Sergey Zozulya |
|
| 16:15 | Paul Vulto Mimetas Organ on Chip Technology in Drug Development |
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| 17:00 | Marián Hajdúch (IMTM) Drug Research and Development: from Molecular Target to Personalized Therapy |
|
| Wednesday September 7th | ||
| 9:00 | Norbert Weiss (IOCB) Trafficking of T-type Calcium Channels in Health and Disease |
|
| 9:45 | Radim Nencka (IOCB) Rational Drug Design of Novel PI4K Inhibitors |
|
| 10:30 | Coffee break | |
| 10:45 | Mathias Frederiksen (Novartis) Chemical Genetics |
|
| 11:30 | František Štěpánek (UCT) Remotely Controlled Release and In-situ Production of Pharmaceutically Active Substances Using Chemical Micro-robots |
|
| 12:15 | Piotr Golkiewicz Elseviere Life Science Solutions from Elsevier Supporting the Process of Drug Development from early Discovery to Post-marketing Phase by Delivering Fast and Comprehensive Scientific Information |
|
| 13:00 | Lunch | |
| 14:00 | IOCB tour followed by City tour and dinner | |
| Thursday September 8th | ||
| 9:00 | Pavlina Rezacova (IOCB) X-ray Crystallography and Structure-based Drug Design |
|
| 9:45 | Václav Veverka (IOCB) Biomolecular NMR in Knowledge-based Drug Design |
|
| 10:15 | Coffee break | |
| 10:30 | Vojtěch Spiwok (UCT) Potential of Biomolecular Simulations in Drug Design |
|
| 11:45 | Josef Klima Pharmakl Bioanalytics in Drug Development |
|
| 12:30 | Lunch | |
| 13:30 | David M. Andrews (Astra Zeneca) Discovery of AZD9496: an oral, selective estrogen receptor downregulator (SERD) for the treatment of breast cancer. |
|
| 14:15 | Vít Perlik (Pharminvent) Clinical research in inhalation drug development |
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| 15:00 | Stephan Bachmann (Roche) Process of API synthesis |
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| 15:45 | UCT tour, UCT brewery | |
| Friday September 9th | ||
| 9:00 | Martin Fusek (Institute of Organic Chemistry and Biochemistry AS CR, v.v.i.) Easy - Biodrugs – Overview |
|
| 9:45 | Christian Heinis (EPFL Lausanne) Peptide Macrocycle Drugs |
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| 10:30 | Coffee break | |
| 10:45 | Martin Šícho (UCT) Exploring Chemical Space for Drug Discovery |
|
| 11:30 | Igor Linhart (UCT) Designer Drugs: From Cul de Sacs of Pharmaceutical Research to the Illicit Street Drugs |
|